2012
ASCO-2012 Genitourinary Cancers Symposium
J. R. Osborne1, N. Hassan1, S. Vallabhajosula1, A. Nikolopoulou1, K. Maresca2, S. Hillier2, J. Joyal2, R. Crummet2, T. Armor2, S. Tagawa1, S. Goldsmith1, J. Babich2.
Tc-99m Labeled Small Molecular Inhibitors of Prostate Specific Membrane Antigen (PSMA): New Molecular Imaging Probes to Detect Metastatic Prostate Adenocarcinoma (PCa).
February 3, 2012
1New York Weill Cornell Medical Center, New York, NY; 2Molecular Insight Pharmaceuticals, Inc. Cambridge, MA
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2011
Annual Congress of the European Association of Nuclear Medicine
S. Vallabhajosula1, J. Osborne1, A. Nikolopoulou1, K. Maresca2, R. Crummet2, T. Armor2, J. Barrett2, S. Tagawa1, S. Goldsmith1, J. Babich2. Novel 99mTc-labeled Small Molecule Inhibitors of Prostate Specific Membrane Antigen (PSMA): Initial experience in healthy volunteers and men with metastatic prostate adenocarcinoma (PCa).
October 18, 2011
1Weill Cornell Medical College, Cornell University New York Presbyterian Hospital, New York, NY; 2Molecular Insight Pharmaceuticals, Inc., Cambridge, MA
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Society of Nuclear Medicine 2011 Annual Meeting
Hillier, Shawn M; Lu, Genliang; Maresca, Kevin P; Marquis, John C; Zimmerman, Craig N; Eckelman, William C; Joyal, John L; Babich, John W. Molecular Imaging of Tumor Carbonic Anhydrase (CA) with a 99mTc-labeled Small Molecule Inhibitor.
Abstract 243, June 6, 2011
Molecular Insight Pharmaceuticals, Inc., Cambridge, MA
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Hillier, Shawn M1; Merkin, Ross1; Maresca, Kevin P1; Zimmerman, Craig N1; Barrett, John A1; Tesson, Mathias2; Eckelman, William C1; Mairs, Rob2; Joyal, John L1; Babich, John W1. 131I MIP-1375, a Small Molecule Prostate-Specific Membrane Antigen (PSMA) Inhibitor for Targeted Therapy of Prostate Cancer (PCa).
Abstract 361, June 7, 2011
1Molecular Insight Pharmaceuticals, Inc., Cambridge, MA; 2Centre of Oncology and Applied Pharmacology, University of Glasgow, Glasgow, Scotland, UK.
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Marquis, John C1; Maresca, Kevin P1; Lu, Genliang1; Hillier, Shawn M1; Zimmerman, Craig N1; Reubi, Jean C 2; Maecke, Helmut3; Eckelman, William C1; Joyal, John L1; Babich, John W1. Comparison of SSTR2 Agonist and Antagonist Peptides Incorporating a Novel 99mTc-Chelator for Targeting Neuroendocrine Tumors.
Abstract 472, June 7, 2011
1Molecular Insight Pharmaceuticals, Inc., Cambridge, MA; 2Institute of Pathology, University of Bern, Bern, Switzerland; 3Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany.
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2010
European Association of Nuclear Medicine Annual Congress
Barrett JA1, LaFrance ND1, Armor T1, Goldsmith SJ2, Vallabhajosula2 S, Kipper SL3, Maresca K1, Femia F1, Stubbs JB3, Stabin MG, Joyal JL1, Babich JW1. Detection of metastatic prostate cancer (PCa) in Soft Tissue, Bone, and Prostate with 123I-MIP-1072: A Comparison with 111In-Capromab Pendetide.
Abstract: OP334, October 11, 2010
1Molecular Insight Pharmaceuticals, Cambridge, MA; 2Weill Medical College of Cornell University; 3 Radiation Dosimetry Services, Inc.
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Hillier SM1, Maresca KP1, Merkin RD1, Tesson M2, Barrett, JA1, Mairs R2, Eckelman WC3, Joyal JL1, Babich JW1. Inhibition of Human Prostate Cancer Growth by Targeting Prostate Specific Membrane Antigen (PSMA) using an I-131 labeled small molecule inhibitor.
Abstract: OP552, October 13, 2010
1Molecular Insight Pharmaceuticals, Cambridge, MA; 2University of Glasgow; Molecular Tracers, LLC3
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Society of Nuclear Medicine 2010 Annual Meeting
Hillier SM, Kern AM, Maresca KP, Marquis JC, Femia FJ, Zimmerman CN, Eckelman WC, Joyal JL, Babich JW. Molecular Imaging for Monitoring Prostate Cancer Response to Paclitaxel
Abstract #14. SNM Annual Meeting. 2010. June 6
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Maresca KP, Hillier SM, Lu G, Marquis JC, Zimmerman CN, Eckelman WC, Joyal, JL, Babich, JW. Influence of Functionalized Chelators on Affinity and Pharmacokinetics of 99mTc(CO)3-Labeled Small Molecules Targeting Prostate Specific Membrane Antigen (PSMA). Abstract #250. SNM Annual Meeting. 2010. June 7
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Hillier SM1, Maresca KP1, Lu G1, Marquis JC1, Zimmerman CN1, Nimmagadda S2, Eckelman WC1, Pomper MG2, Joyal JL1, Babich JW. 99mTc-MIP-1340, a Small Molecule Inhibitor of PSMA for Molecular Imaging of Prostate Cancer. Abstract: #481. SNM Annual Meeting. 2010 June 8 1Molecular Insight Pharmaceuticals, Inc., Cambridge, MA, 2Johns Hopkins Medical Institute, Baltimore, MD
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Marquis JC1, Maresca KP1, Lu G1, Hillier SM1, Zimmerman CM1, Dhara S 2, Eckelman WC1, Pomper MG2, Joyal JL1, Babich JW1 Evaluation of 99mTc-MIP-1407, an Octreotide Analog for Targeting Neuroendocrine Tumors. Abstract #482. SNM Annual Meeting. 2010. June 8 1Molecular Insight Pharmaceuticals, Inc., Cambridge, MA, 2Johns Hopkins Medical Institute, Baltimore, MD.
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2009
Barrett JA. Biomarkers in the diagnosis, staging and treatment of cancer-Personalized Medicine, American Association of Pharmaceutical Scientists, Annual Meeting. 2009 June 21
Barrett JA, LaFrance, ND, Coleman RE, Goldsmith SJ, Stubbs JB, Petry N, Vallabhajosula S, Maresca KP, Femia F, Stabin M, Babich JW. Targeting Metastatic Prostate Cancer (PCa) in Patients using 123I-MIP 1072 & 123I-MIP 1095. Abstract #522. SNM Annual Meeting. 2009 June 16
Maresca KP, Hillier SM, Lu G, Marquis JC, Zimmerman CN, Eckelman, WC, Joyal JL, Babich JW.
Molecular Targeting using Advanced Single Amino Acid Chelates (SAAC) for 99mTc. Abstract #146. SNM Annual Meeting. 2009 June 15.
Joyal JL. Novel Small Molecules for Imaging Soft Tissue and Bone Metastasis in Prostate Cancer, International Symposium on Cancer Metastasis and Lymphovascular System: Basis for Rational Therapy. 2009 May 7
2008
Joyal JL, Hillier SM, Marquis JC, Chen J, Friebe M, Dinkelberg L, Boyd M, Mairs R, Barrett JA, Kronauge JF, Babich JW. Molecular Targeting of Melanoma With Radiolabeled Benzamides. Abstract #61. SNM Annual Meeting. 2008 June 15.
Marquis JC, Hillier SM, Besanger T, Kronauge JF, Barrett JA, Anderson TL, Irwin DJ, Norenberg JP, Joyal JL, Babich JW. Comparative Analysis of 111Inedotreotide, 90Y-edotreotide and 111Inpentetreotide in vivo and in vitro. Abstract #63. SNM Annual Meeting. 2008 June 15.
Hillier SM, Maresca KP, Femia FJ, Zimmerman CN, Barrett JA, Foss CA, Eckelman WC, Pomper MG, Joyal JL, Babich JW. Small molecule PSMA inhibitors for targeted molecular imaging of prostate cancer. Abstract #389. SNM Annual Meeting. 2008 June 17.
Femia FJ, Maresca KP, Hillier SM, Marquis JC, Luss-Lusis E, Zimmerman CN, Joyal JL, Abeysekera B, Kronauge JF, Babich JW. [123I]MIP-1095 for targeting prostate cancer via prostate specific membrane antigen (PSMA): A high specific activity radio-synthesis. Abstract #393. SNM Annual Meeting. 2008 June 17.
2007
Barret JA, Coleman RE, Morse MA, Borys N, Kronauge JF, Stubbs JB, Mok H, Qi J, Petry N, Vaidyanathan G, Babich JW. Radiation Dosimetry, and Clearnace of no carrier-added 131I-MIBG (Ultratrace) in Seven Carcinoid and Four Pheochromocytoma Patients. EANM Annual Congress. 2007
Udelson JE, Bateman T, Spiegler E, Bergmann S, Iskandrian A, Mahmarian J, Heller Gary, Kontos M, Ziffer J, Borys N, LaFrance N, Babich J, Garcia E. Phase 2B Study of the Safety and Efficacy of [123I]-BMIPP for Identification of Ischemic Myocardium Using SPECT in Adults Admitted to the ED for Evaluation of an Acute Coronary Syndrome. ASNC Annual Meeting. 2007 September 8.
Folks RD, Garcia EV, Verdes L, Armor T, Borys N, Udelson JE. Development and Restrospective Validation of a Risk-Adjusted, Gender-Matched Normal Database for I-123 BMIPP SPECT. ASNC Annual Meeting. 2007 September 6.
Kronauge JF, Barrett JA, Qi J, Mok H, Hunter DH, Bensimon C, Oelsner S, Norenberg JP, Anderson T, Gallo S, Hillier, SM, Joyal J, Lee NS, Babich JW. Formulation Comparisons and Pharmacokinetics of High Specific Activity Ultratrace 131I-Iobenguane (mIBG) for Therapy. SNM Annual Meeting. 2007 June
Yokell DL, Kronauge JF, Kao C, Babich JW. Abstract 1835: A Comparison of Iodine-123 & Technetium-99m assays using Dose Calibrators. SNM Annual Meeting. 2007 June.
Femia FJ, Maresca KP, Hillier SM, Zimmerman CN, Joyal JL, Barrett JA, Coleman T, Aras O, Foss CA, Pomper MG, Dilsizian V, Eckelman WC, Babich JW. Synthesis and Evaluation of a Series of M(CO)3+ [M = Tc, Re] Lisinopril Complexes for Imaging Angiotensin Converting Enzyme (ACE). Abstract #613. SNM Annual Meeting. 2007 June 6
Maresca KP, Hillier SM, Femia FJ, Barone C, Joyal JL, Zimmerman CN, Barrett JA, Foss CA, Eckleman WC, Pomper MG, Babich JW. Molecular Targeting of Prostate Cancer With Small Molecule Inhibitors of Prostate Specific Membrane Antigen (PSMA). Abstract #84. SNM Annual Meeting. 2007 June 3.